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Ulrich Grau,
Ph.D.
Founder, President & Chief Executive Officer
Dr.
Grau is the President and Chief Executive Officer of Lux Biosciences, Inc. Dr.
Grau brings 25 years of experience from the biotechnology and pharmaceutical
industry to the company. His extensive expertise in the healthcare field
includes general and R&D management, corporate strategy and strategic
alliances, and the development of new products and technologies for a
variety of diseases.
Dr. Grau served as Enzon’s Chief Scientific Officer from 2002 to January
2005. In this role, he upgraded Enzon’s R&D capabilities and built a rich
portfolio of projects in all stages of development, based on Enzon’s
macromolecular engineering technologies (Single Chain Antibodies [SCAs] and
PEGylation) and based on partnering. The areas of therapeutic focus included
oncology and immunology, as well as viral and fungal infections.
Prior to joining Enzon Dr. Grau served as President of Research and
Development and member of the Executive Board at BASF Pharma/ Knoll where he
directed a global R&D organization and significantly advanced and expanded
the Company’s product portfolio. This included therapies for autoimmune
diseases, obesity, arrhythmia, sepsis, severe pain, and most notably, a
human antibody directed against TNF-α (adalimumab, Humira®)
for the treatment of rheumatoid arthritis and other autoimmune diseases.
Previously, Dr. Grau served as Senior Vice President and R&D Integration
Officer of Aventis Pharma, and as SVP Global Product Realization at Hoechst
Marion Roussel, where he directed the company’s global late-stage product
development activities with a portfolio of projects ranging from diabetes,
infectious diseases, oncology, neurology, osteoporosis, cardiology,
rheumatology, and hormone replacement therapies, and a budget of $940
million. During 1996-97, Dr. Grau was CEO of Hoechst Marion Roussel in the
Netherlands, responsible for the entire commercial infrastructure of this
subsidiary. Insulin Glargine (Lantus®)
is based on his inventions at the beginning of his career at Hoechst.
Dr. Grau received his Ph.D. in chemistry and biochemistry from the
University of Stuttgart and spent three years as a post-doctoral fellow at
Purdue University in the field of protein crystallography.
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